Anti-Acne and Antioxidant Serum (Skincare) (30 mL)

Ingredients:

  • Clove Terpene Natural Isolate Oil – 0.3 mL (1%)
  • Jojoba Oil – 21 mL (70%)
  • Tea Tree Oil – 0.6 mL (2%)
  • Vitamin E – 0.3 mL (1%)
  • Aloe Vera Gel – 7.8 mL (26%)

Directions:

  1. Mix 0.3 mL clove terpene with 0.6 mL tea tree oil and 0.3 mL vitamin E (total 1.2 mL essential mix) into 21 mL jojoba oil.
  2. Add 7.8 mL aloe vera gel, stir until homogeneous (final total 30 mL).
  3. Store in a dark bottle.

Use 2–3 drops at night, store in cool place, shelf life 3 months.


Soothing Lotion for Irritated Skin (Personal Care) (100 mL)

Ingredients:

  • Clove Terpene Natural Isolate Oil – 0.5 mL (0.5%)
  • Shea Butter – 20 mL (20%)
  • Virgin Coconut Oil – 30 mL (30%)
  • Witch Hazel – 40 mL (40%)
  • Lavender Essential Oil – 1 mL (1%)
  • Distilled Water – 8.5 mL (8.5%)

Directions:

  1. Melt 20 mL shea butter and 30 mL coconut oil (total liquid base ~50 mL), then mix with 0.5 mL clove terpene and 1 mL lavender.
  2. Add 40 mL witch hazel and 8.5 mL distilled water; emulsify using a mixer until reaching 100 mL.
  3. Cool and store in a glass jar.

Apply a thin layer after showering, avoid eyes, shelf life 2 months refrigerated.


Anti-Aging Face Oil (Skincare) (50 mL)

Ingredients:

  • Clove Terpene Natural Isolate Oil – 0.75 mL (1.5%)
  • Argan Oil – 30 mL (60%)
  • Rosehip Oil – 10 mL (20%)
  • Frankincense Essential Oil – 1 mL (2%)
  • Vitamin E – 0.5 mL (1%)
  • Fractionated Coconut Oil – 7.75 mL (15.5%)

Directions:

  1. Start with 30 mL argan oil as the base, add 0.75 mL clove terpene, 1 mL frankincense oil, and 0.5 mL vitamin E (total essential ~2.25 mL).
  2. Mix with 10 mL rosehip oil and 7.75 mL fractionated coconut oil until reaching 50 mL; shake well.
  3. Store in a dropper bottle.

Apply 4–5 drops morning/night, store in dark place, shelf life 4 months.


Topical Analgesic Balm (Basic Pharmacy) (50 mL)

Ingredients:

  • Clove Terpene Natural Isolate Oil – 1 mL (2%)
  • Beeswax – 10 mL (20%)
  • Shea Butter – 20 mL (40%)
  • Virgin Coconut Oil – 17.5 mL (35%)
  • Menthol Crystals – 0.5 mL (1%)
  • Eucalyptus Essential Oil – 1 mL (2%).

Directions:

  1. Melt 10 mL beeswax, 20 mL shea butter, and 17.5 mL coconut oil in a water bath (total liquid base ~47.5 mL).
  2. Add 1 mL clove terpene, 0.5 mL menthol crystals, and 1 mL eucalyptus oil; mix well until total equals 50 mL.
  3. Pour into a metal tin, cool.

Apply thinly to painful areas (avoid direct eye/mouth contact), store in cool place, shelf life 3 months.


Cooling Toner Spray (Personal Care) (100 mL)

Ingredients:

  • Clove Terpene Natural Isolate Oil – 0.5 mL (0.5%)
  • Witch Hazel – 50 mL (50%)
  • Rose Water – 40 mL (40%)
  • Glycerin – 5 mL (5%)
  • Peppermint Essential Oil – 0.5 mL (0.5%)
  • Distilled Water – 4 mL (4%).

Directions:

  1. Mix 0.5 mL clove terpene and 0.5 mL peppermint oil into 50 mL witch hazel (total essential 1 mL).
  2. Add 40 mL rose water, 5 mL glycerin, and 4 mL distilled water; shake until reaching 100 mL.
  3. Store in a spray bottle.

Spray after washing your face, let dry naturally, keep refrigerated, shelf life 1 month.

Antimicrobial and Anti-Acne

  • Effective against pathogenic bacteria such as Propionibacterium acnes
  • Reduces breakouts and skin inflammation
  • Ideal for anti-acne serums or lotions.

Antioxidant and Cellular Protection

  • Neutralizes free radicals
  • Prevents premature aging and UV damage
  • Suitable for anti-aging creams or moisturizers.

Soothing and Anti-Inflammatory

  • Calms irritated skin, eczema, or post-procedure (such as laser)
  • Used in soothing balms or masks to reduce redness.

Aroma Booster and Fixative

  • Provides warm woody-spicy aroma stability in perfumes, soaps, or deodorants
  • Low volatility for long-lasting effects without irritation.

Natural Antimicrobial

  • As a preservative in shampoos, face washes, or body washes
  • Combats fungi and bacteria on the skin
  • Supports clean beauty formulations.

Sensory Enhancer

  • Improves texture and aroma in topical products such as scrubs or oil blends
  • Safe for daily use with non-comedogenic properties.

Analgesic and Anti-Inflammatory

  • Relieves chronic pain and inflammation (e.g., arthritis)
  • Used in topical gels or oral capsules.

Antibacterial and Antifungal

  • Active against resistant pathogens such as Helicobacter pylori or skin fungi
  • Potential for oral care products or antimicrobial supplements.

Anti-Cancer and Neuroprotective

  • Inhibits tumor cell proliferation and protects nerve cells; under study for nutraceutical formulations or cancer-preventive drugs.
  1. Chemical Composition and Content of Essential Oil from the Buds of Turkish Clove (Syzygium aromaticum L.) - BioResources
  2. Effect of β-caryophyllene from Cloves Extract on Helicobacter pylori Eradication in Mouse Model – PubMed
  3. Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health - MDPI
  4. Clove Essential Oil: Chemical Profile, Biological Activities, Encapsulation Strategies, and Food Applications - MDPI
  5. Chemical profiling of clove bud oil (Syzygium aromaticum) from Toli-Toli and Bali by GC-MS analysis – Research Gate
  6. Beta-Caryophyllene, a Cannabinoid Receptor Type 2 Selective Agonist, in Emotional and Cognitive Disorders - MDPI
  7. (−)-β-Caryophyllene, a CB2 Receptor-Selective Phytocannabinoid, Suppresses Motor Paralysis and Neuroinflammation in a Murine Model of Multiple Sclerosis - MDPI
  8. Clove (Syzygium aromaticum): a precious spice - PubMed
  9. Clove: A review of a precious species with multiple uses - International Journal of Chemical and Biochemical Sciences
  10. Type and morphological character of local clove (Syzygium aromaticum) from Maluku, Indonesia - Biodiversitas Journal of Biological Diversity
  11. Morphological Traits of Maluku Native Forest Clove (Syzygium aromaticum L. Merr & Perry) - Jurnal Agro
  12. The Effect of Clove (Syzygium Aromaticum L.) Cropping Patterns on Understory Species Diversity and Spatial Heterogeneity - SSRN
  13. Smart agroforestry for sustaining soil fertility and community livelihood - Agroforestry Systems
  14. Syzygium aromaticum L. (Myrtaceae): Traditional Uses, Bioactive Chemical Constituents, Pharmacological and Toxicological Activities - MDPI
  15. A Comprehensive Review of Clove (Syzygium aromaticum) with Special References of Ayurvedic and Modern Sciences - International Journal of Pharmaceutical Research and Applications
  16. Bioactive properties of clove (Syzygium aromaticum) essential oil nanoemulsion: A comprehensive review - PubMed
  17. Spice Up Your Skincare: Clove Bud Essential Oil’s Surprising Benefits for Skin Health – Bulk Naturals
  18. Terpenes and Essential Oils in Pharmaceutics: Applications as Therapeutic Agents and Penetration Enhancers with Advanced Delivery Systems for Improved Stability and Bioavailability - MDPI
  19. Chemical composition, antioxidant and the possible use as skin-care ingredient of clove oil ( Syzygium aromaticum (L.) Merr. & Perry) and citronella oil ( Cymbopogon goeringii ) from China – ResearchGate
  20. Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health and potential application as natural food preservatives - PubMed
  21. Gel for topical application of clove essential oil with broad spectrum anti-inflammatory action and method of preparing same - Patents
  22. The Science Behind Clove Oil's Efficacy in Skincare and Oral Care - Nbinno
  23. Neuroprotective Properties of Clove (Syzygium aromaticum): State of the Art and Future Pharmaceutical Applications for Alzheimer's Disease - PubMed
  24. Syzygium aromaticum (clove buds) as a natural antibacterial agent: a promising alternative to combat multidrug-resistant bacteria - PubMed
  25. Syzygium aromaticum Phytoconstituents Target SARS-CoV-2: Integrating Molecular Docking, Dynamics, Pharmacokinetics, and miR-21 rs1292037 Genotyping - PubMed
  26. The Effects of Clove and Its Constituents on Reproductive System: a Comprehensive Review - PubMed
  27. Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells - PubMed
  28. Disentangling the ecotoxicological selectivity of clove essential oil against aphids and non-target ladybeetles - PubMed
  29. Characterisation and quantification of phenolic, anthocyanidin and terpene species in plant foods and plant food-based complementary products with antioxidant and neuroprotective properties – PubMed
  30. GREEN BEAUTY RECIPES: Easy Homemade Recipes to Make Your Own Organic and Natural Skincare, Hair Care and Body Care Products - DokumenPUB
  31. Making DIY Cosmetics with Herbs and Essential Oils for Skin Care - Tofillo
  32. Spice Up Your Skincare: Clove Bud Essential Oil’s Surprising Benefits for Skin Health – Bulk Naturals
  33. How To Make Clove Oil At Home & Brighten Your Skin - Anveya

Halal Certificate: 33110034666001125

Export Documentation Available

  • Certificate of Analysis (COA)
  • Material Safety Data Sheet (MSDS)
  • Phytosanitary Certificate
  • Halal Certificate
  • CITES permit (required for international trade)

Not a medicinal product. Not intended to replace professional diagnosis or medical treatment. Individual results may vary.

Anti-Inflammatory and Analgesic

  • Reduces cytokine inflammation and relieves chronic pain, such as arthritis or toothache
  • Effective as a natural alternative for topical treatments.

Antimicrobial and Antifungal

  • Active against multidrug-resistant bacteria (such as Staphylococcus aureus) and pathogenic fungi
  • Potential for treating skin, oral, or digestive infections, including Helicobacter pylori.

Antioxidant and Neuroprotective

  • Protects cells from oxidative stress, supports nerve health, and reduces neuronal damage
  • Beneficial for preventing neurodegenerative diseases such as Alzheimer's or Parkinson’s.

Antiviral and Antiparasitic

  • Inhibits viral replication such as SARS-CoV-2 through viral protein inhibition
  • Effective against parasites, supporting therapy for tropical infections.

Anti-Cancer

  • Inhibits tumor cell proliferation and triggers apoptosis
  • Being researched for breast and colorectal cancer treatment as adjuvant therapy.

Effects on Reproductive System

  • May support fertility by reducing oxidative stress on reproductive cells, although effects vary (contradictory at high doses).

CLOVE TERPENE NATURAL ISOLATE OIL By DDISTILLERS

Brand: DDistillers

INCI name: Clove Terpene

Product Category: Single natural isolate, purity: 100%

Barcode: -

HS Code: 33019090

CAS#:

FEMA#: -

Extraction method: Fractional Distillation


PRODUCT DESCRIPTION

Clove Terpene Natural Isolate Oil is a natural terpene isolate extracted from clove essential oil (Syzygium aromaticum) through fractional distillation, a distillation method that separates components based on differences in boiling points to achieve high purity without thermal degradation. This process begins with steam distillation of cloves to obtain raw essential oil, then precisely fractionated to isolate the pure terpene fraction with sesquiterpene concentrations up to 90%, minimizing contaminants such as eugenol.

Organoleptic Characteristics:

·         Color: Yellow to brown liquid.

·         Aroma: Woody-spicy, peppery with warm, earthy, slightly spicy clove-like nuances that are soothing.

·         Texture: Light to medium liquid, low volatility, with slow evaporation for long-lasting and stable aromatic effects.

Composition:

Clove terpene is dominated by β-caryophyllene (≥70%) as the main sesquiterpene, accompanied by α-humulene (5–10%) and other minor terpenes, functioning as a non-psychoactive cannabinoid through interaction with CB2 receptors for anti-inflammatory modulation and reduction of oxidative stress. This compound also exhibits strong antimicrobial activity against pathogenic bacteria, antioxidant properties for cellular protection, as well as muscle-relaxant and neuroprotective effects, consistent with the traditional use of cloves in Southeast Asian herbal medicine. This isolate is ideal for cosmetics and personal care formulations such as perfume fixatives, anti-acne lotions, aromatherapy soaps, or soothing creams, where it enhances aroma stability, supports natural claims, and provides long-term grounding effects with high bioavailability.


BOTANICAL & MORPHOLOGY

Clove terpene primarily originates from plants of the Myrtaceae family, specifically Syzygium aromaticum (clove) in the tropical regions of Indonesia, especially the Maluku Islands as the native habitat. Syzygium aromaticum is an evergreen tree with wide distribution in humid tropical climates, including Indonesia, India, Madagascar, Tanzania, Sri Lanka, and Brazil, cultivated intensively in agroforestry plantations. This plant grows optimally in warm tropical climates (average temperature 20–30°C, rainfall 1,500–2,500 mm/year), in fertile volcanic, loamy, or lateritic soils that are loose and well-drained with pH 5–7 and an elevation of 0–1,000 masl.

Botanical characteristics of Syzygium aromaticum:

  • Habit: Evergreen tree 5–20 meters tall (commonly 8–12 m), with straight trunk and broad rounded or dense conical crown; semi-erect and low branches, often pruned to facilitate flower bud harvesting; deep taproot for stability in hilly soils.
  • Trunk & bark: Trunk diameter up to 30–60 cm, grayish-brown bark that peels in thin plates; reddish resinous sap containing phenolic compounds such as eugenol and sesquiterpenes (including β-caryophyllene as precursor of clove terpene).
  • Leaves: Simple, opposite or alternate, elliptic-lanceolate (length 8–18 cm, width 4–7 cm), glossy green surface above and paler beneath with pinnate veins; containing essential oil glands that produce terpenes as chemical defense against pathogens.
  • Flowers: Hermaphroditic, arranged in terminal panicles 5–15 cm long; flower buds nail-shaped (1–2 cm long), light green turning pink before blooming; small flowers with 4 green petals, 4 sepals, and many yellowish-white stamens; mainly pollinated by insects such as bees during the dry season, with young buds being the main source of clove terpene (sesquiterpene fraction up to 15–20% in essential oil).
  • Fruit: Round or elliptical berry (1–2 cm diameter), red to dark purple when ripe, containing a single seed; although the fruit is rarely harvested, flower buds are collected before blooming to produce essential oil rich in terpenes such as β-caryophyllene (≥70% in terpene isolate fraction).

Ecology & Distribution:

Syzygium aromaticum grows naturally in lowland tropical rainforests or mixed plantations in the Maluku region (Indonesia) as an endemic species, now widely distributed across global wet tropical zones through the spice trade since the 16th century. The plant tolerates partial shade, high humidity, and acidic soil, playing a role in agroforestry ecosystems as a shade tree supporting crop diversification and preventing erosion on volcanic slopes. Clove terpene, as the volatile fraction of clove, functions in plant defense against herbivores, pathogenic fungi, and environmental stress through natural antimicrobial properties, as well as attracting insect pollinators through its strong spicy aroma.

Ecological Role:

  • Provides habitat for wildlife, including Maluku endemic birds and pollinating insects, through dense canopy offering protection and food sources.
  • Deep root systems and wide canopy prevent soil erosion in landslide-prone hilly areas and improve soil fertility through nutrient-rich leaf litter.
  • Sap and terpene compounds support soil microbial biodiversity and regulate plant competition through allelopathic effects, while contributing to the conservation of native Indonesian spices through organic plantations.

HISTORY & TRADITIONAL USE

Clove terpene, as a natural sesquiterpene fraction extracted from clove essential oil (Syzygium aromaticum)—primarily β-caryophyllene (≥70%) and α-humulene—has a long historical record as part of traditional medicine and spice trade in the tropical regions of Asia. Originating from the Maluku Islands (Spice Islands) in Indonesia as its native habitat, cloves and their terpene fractions have been used since the Han Dynasty in China (around 200 BC) as “chicken-tongue spice” to relieve toothache, digestive issues, and as a warm antiseptic, either through direct clove chewing or essential oil infusion.

In the Indian Ayurvedic system (around 1500 BC), clove terpene—rich in β-caryophyllene up to 15–20%—was recommended to balance vata and kapha doshas, treat arthritis, asthma, intestinal infections, and nausea, thanks to its natural anti-inflammatory and antimicrobial properties. Meanwhile, indigenous communities of Southeast Asia and ancient China used it for wounds, mouth pain, and respiratory support, with Hippocrates in Ancient Greece (around 400 BC) documenting the use of similar spices for digestive and respiratory issues.

During the Middle Ages, clove terpene became a key commodity in Portuguese and Dutch spice trade (16th century), spreading into Europe as a component of balms, theriac detoxification formulations, food preservatives, and royal perfumes—helping to combat plagues and maintain aroma stability. Scientific advancements began in the 1830s when French chemists isolated eugenol from clove essential oil through steam distillation, followed by the separation of specific terpene fractions in the early 20th century; the structure of β-caryophyllene was determined in the 1960s via spectroscopy, and pharmacological research in the 1970s uncovered its interaction with type 2 cannabinoid receptors (CB2), making it a non-psychotropic phytocannabinoid for immune modulation without euphoric effects.

In the post-2000 era, clove terpene became widely recognized in modern applications, including cosmetics as an aroma fixative and antimicrobial agent in anti-acne lotions, as well as nutraceuticals for managing non-alcoholic fatty liver disease and neuroprotective effects. Today, alongside the trend of plant-based therapies, it is being studied for anti-cancer and anti-inflammatory treatments, bridging the traditional spice heritage of Maluku with contemporary innovations in pharmaceuticals and personal care.


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Specification
Source of Material

Source Material: Essential oils derived from cloves oil (Syzygium aromaticum).

Origin: Indonesian

Cultivation

Conventionally harvested and periodically replanted to ensure sustainability

Main Content

β-Caryophyllene (≥70%), α-Humulene (5-10%), as well as minor terpenes such as trace eugenol (<5%) and other sesquiterpenes

Organoleptik
  • Color: Colorless to pale yellow.
  • Aroma: Woody-spicy, peppery with warm, earthy, and slightly spicy clove-like undertones.
Solubility

Insoluble in water but soluble in alcohol (such as ethanol), essential oils, and organic solvents.

Blend well

pencampuran dengan bahan berbasis air tanpa emulsifier

Compatible with other terpenes (e.g., pinene, limonene), spice essential oils (e.g., cinnamon, nutmeg), or carrier oils (e.g., jojoba, sweet almond oil). Avoid mixing with water-based ingredients without an emulsifier.

Downstream product application

Cosmetics and Personal Care Formulation 

Shelf Life

5 years

Storage instructions

Store in a cool (below 25 °C), dry, and dark place. Keep tightly sealed to prevent oxidation and volatilization.

Allergies and general precautions
  • Conduct a patch test 24 hours before use. May cause irritation or allergic reactions.
  • Avoid eye contact and prolonged inhalation (>100 ppm). Rinse with water if irritation occurs.
  • Flammable—keep away from flames and heat sources.

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